Product Datasheet  
CASP2 Antibody  
Catalog Number: 31011  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P38936
    Gene ID:1026
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to N terminal 201 amino acids of Human Caspase-2
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 51kd
    ELISA: 1:1000-1:10000
    Western blotting: 1:1000-1:2000
    Immunohistochemistry: 1:100-1:300
  • other_names：  
  • Caspase-2, ICH1, NEDD2, CASP-2, NEDD-2
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CASP2 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.



 
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