1-832-868-1888
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Catalog Number: |
30751 |
| other_names: | FKBP3; FKBP-25; FKBP-3; FKBP25; PPIase; FK506 binding protein 3 |
Amount: |
100μg |
| calculated_mw: | 30kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q00688 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human FKBP3 (NP_002004.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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