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FKBP3 Polyclonal Antibody

Catalog Number:

30751
other_names: FKBP3; FKBP-25; FKBP-3; FKBP25; PPIase; FK506 binding protein 3

Amount:

100μg
calculated_mw: 30kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q00688
NCBI Gene ID:2287

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human FKBP3 (NP_002004.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:100

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