Product Datasheet
FKBP3 Polyclonal Antibody
Catalog Number: 30751
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q00688
NCBI Gene ID:2287
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human FKBP3 (NP_002004.1).
- appl_detail:
- WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:100
- other_names:
- FKBP3; FKBP-25; FKBP-3; FKBP25; PPIase; FK506 binding protein 3
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
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