Product Datasheet  
FKBP3 Polyclonal Antibody  
Catalog Number: 30751  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q00688
    NCBI Gene ID:2287
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fusion protein of human FKBP3 (NP_002004.1).
  • reactivity:  
  • Human
  • appl_detail:  
  • WB 1:500 - 1:2000
    IF 1:50 - 1:100
    IP 1:50 - 1:100
  • other_names:  
  • FKBP3; FKBP-25; FKBP-3; FKBP25; PPIase; FK506 binding protein 3
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB,IF
  • Background:  
  • The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.



 
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