SAP18 Polyclonal Antibody

Catalog Number:

30559

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O00422
NCBI Gene ID:10284

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SAP18 (NP_005861.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

References:

appl_detail:

WB 1:200 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Datasheet PDF