Product Datasheet  
SAP18 Polyclonal Antibody  
Catalog Number: 30559  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O00422
    NCBI Gene ID:10284
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human SAP18 (NP_005861.2).
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:200 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • other_names：  
  • SAP18; 2HOR0202; SAP18P; Sin3A associated protein 18
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IHC,IF
  • Background：  
  • Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.



 
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