Product Datasheet  
NBR1 Polyclonal Antibody  
Catalog Number: 30504  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q14596
    NCBI Gene ID:4077
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human NBR1
  • reactivity:  
  • Human,Mouse,Rat,Monkey
  • appl_detail:  
  • WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:100
    IP 1:20 - 1:50
  • other_names:  
  • NBR1; 1A1-3B; IAI3B; M17S2; MIG19; next to BRCA1 gene 1 protein
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB,IHC,IF
  • Background:  
  • The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.



 
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