Product Datasheet
SKAP1 Polyclonal Antibody
Catalog Number: 30445
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q86WV1
NCBI Gene ID:8631
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SKAP1 (NP_001068567.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- SKAP1; HEL-S-81p; SCAP1; SKAP55; src kinase-associated phosphoprotein 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
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