Product Datasheet
RELA Antibody
Catalog Number: 31102
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P01303
Gene ID:4852
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Full length fusion protein
- appl_detail:
- Predicted MW: 25kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
- other_names:
- v-rel reticuloendotheliosis viral oncogene homolog A (avian), p65, NFKB3
- Specificity:
- The antibody detects endogenous level of total RELA protein.
- Background:
- NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
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