Product Datasheet  
MUTYH Antibody  
Catalog Number: 31101  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q13232
    Gene ID:4832
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a C terminal 300 amino acids of human mutY homolog (E. coli)
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 60kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • mutY homolog (E. coli), MYH, CYP2C
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total MUTYH protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.



 
© Signalway Biotechnology All Rights Reserved.