Product Datasheet
SLC30A8 Polyclonal Antibody
Catalog Number: 29952
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IWU4
NCBI Gene ID:169026
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SLC30A8 (NP_776250.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- SLC30A8; ZNT8; ZnT-8; zinc transporter 8
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.
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