Product Datasheet
SMPD1 / ASM Polyclonal Antibody
Catalog Number: 29790
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P17405
NCBI Gene ID:6609
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant protein of human SMPD1 / ASM
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
IF 1:50 - 1:100
- other_names:
- SMPD1; ASM; ASMASE; NPD; sphingomyelin phosphodiesterase
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
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