Product Datasheet
ASIC4 Polyclonal Antibody
Catalog Number: 29989
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96FT7
NCBI Gene ID:55515
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ASIC4 (NP_878267.2).
- appl_detail:
- IHC 1:50 - 1:200
- other_names:
- ASIC4; ACCN4; BNAC4; acid-sensing ion channel 4
- Purification:
- Affinity purification
- Background:
- This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
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