Product Datasheet
HIF1A Antibody
Catalog Number: 29547
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q16665
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C/1 year
- Immunogen:
- A synthesized peptide derived from human HIF1a.
- appl_detail:
WB: 1:500-1:3000
IHC: 1:50-1:200
- other_names:
- HIF-1a,HIF1A
- Purification:
- Immunogen affinity purified
- Specificity:
- HIF1a antibody detects endogenous levels of HIF1a.
- Background:
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, Arnt 1 (also designated HIF-1β), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family.
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