Product Datasheet
FREM2 Polyclonal Antibody
Catalog Number: 29525
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5SZK8
NCBI Gene ID:341640
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human FREM2 (NP_997244.4).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- FREM2; FRAS1-related extracellular matrix protein 2
- Purification:
- Affinity purification
- Background:
- This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.
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