Product Datasheet
NOSTRIN Polyclonal Antibody
Catalog Number: 29503
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IVI9
NCBI Gene ID:115677
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human NOSTRIN (NP_001034813.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- NOSTRIN; DaIP2; nostrin
- Purification:
- Affinity purification
- Background:
- Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.
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