Product Datasheet
CDK5RAP2 Polyclonal Antibody
Catalog Number: 28988
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96SN8
NCBI Gene ID:55755
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CDK5RAP2 (NP_060719.4).
- appl_detail:
- WB 1:200 - 1:2000
- other_names:
- CDK5RAP2; C48; Cep215; MCPH3; CDK5 regulatory subunit-associated protein 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
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