Product Datasheet  
PDCD10 Polyclonal Antibody  
Catalog Number: 28949  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9BUL8
    NCBI Gene ID:11235
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human PDCD10 (NP_009148.2).
  • reactivity：  
  • Human,Mouse
  • appl_detail：  
  • WB 1:200 - 1:2000
    IF 1:50 - 1:200
  • other_names：  
  • PDCD10; CCM3; TFAR15; programmed cell death 10
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IF
  • Background：  
  • This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.



 
© Signalway Biotechnology All Rights Reserved.