Product Datasheet  
TCIRG1 Polyclonal Antibody  
Catalog Number: 28940  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q13488
    NCBI Gene ID:10312
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human TCIRG1 (NP_006010.2).
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:200 - 1:2000
    IF 1:50 - 1:200
  • other_names：  
  • TCIRG1; ATP6N1C; ATP6V0A3; Atp6i; OC-116kDa; OC116; OPTB1; Stv1; TIRC7; Vph1; a3; V-type proton ATPase 116 kDa subunit a isoform 3
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IF
  • Background：  
  • This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.



 
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