Product Datasheet  
SIM2 Polyclonal Antibody  
Catalog Number: 28830  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q14190
    NCBI Gene ID:6493
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human SIM2 (NP_033664.2).
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:500 - 1:2000
    IHC 1:100 - 1:200
  • other_names：  
  • SIM2; HMC13F06; HMC29C01; SIM; bHLHe15; single-minded homolog 2
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IHC
  • Background：  
  • This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.



 
© Signalway Biotechnology All Rights Reserved.