Product Datasheet
PTGFR Polyclonal Antibody
Catalog Number: 28822
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P43088
NCBI Gene ID:5737
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human PTGFR (NP_000950.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PTGFR; FP; prostaglandin F receptor
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
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