Product Datasheet
EYA3 Polyclonal Antibody
Catalog Number: 28813
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q99504
NCBI Gene ID:2140
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human EYA3 (NP_001981.2).
- appl_detail:
- WB 1:500 - 1:2000
IF 1:50 - 1:200
- other_names:
- EYA3; eyes absent homolog 3
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
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