Product Datasheet
TCTN1 Polyclonal Antibody
Catalog Number: 28764
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q2MV58
NCBI Gene ID:79600
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human TCTN1 (NP_001076006.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- TCTN1; JBTS13; TECT1; tectonic-1
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.
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