Product Datasheet
BACE2 Polyclonal Antibody
Catalog Number: 28733
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5Z0
NCBI Gene ID:25825
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human BACE2 (NP_036237.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- BACE2; AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP; beta-secretase 2
- Purification:
- Affinity purification
- Background:
- This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
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