Product Datasheet
MTRR Polyclonal Antibody
Catalog Number: 28648
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UBK8
NCBI Gene ID:4552
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MTRR (NP_002445.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MTRR; MSR; cblE; methionine synthase reductase
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.
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