Product Datasheet
CNKSR2 Polyclonal Antibody
Catalog Number: 28628
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8WXI2
NCBI Gene ID:22866
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CNKSR2 (NP_055742.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- CNKSR2; CNK2; KSR2; MAGUIN; connector enhancer of kinase suppressor of ras 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
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