Product Datasheet
SF3A2 Polyclonal Antibody
Catalog Number: 27503
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15428
NCBI Gene ID:8175
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SF3A2 (NP_009096.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- SF3A2; PRP11; PRPF11; SAP62; SF3a66; splicing factor 3A subunit 2
- Purification:
- Affinity purification
- Background:
- This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
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