Product Datasheet
GRIK1 Polyclonal Antibody
Catalog Number: 27452
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P39086
NCBI Gene ID:2897
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GRIK1 (NP_000821.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- GRIK1; EAA3; EEA3; GLR5; GLUR5; GluK1; gluR-5; glutamate receptor ionotropic, kainate 1
- Purification:
- Affinity purification
- Background:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.
© Signalway Biotechnology All Rights Reserved.