Product Datasheet
DPP6 Polyclonal Antibody
Catalog Number: 27328
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P42658
NCBI Gene ID:1804
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DPP6 (NP_001277182.1).
- appl_detail:
- WB 1:1000 - 1:2000
- other_names:
- DPP6; DPL1; DPPX; MRD33; VF2; dipeptidyl peptidase like 6
- Purification:
- Affinity purification
- Background:
- This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants.
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