Product Datasheet
CHRNE Polyclonal Antibody
Catalog Number: 27276
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q04844
NCBI Gene ID:1145
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CHRNE (NP_000071.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:1000 - 1:4000
- other_names:
- CHRNE; ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS; acetylcholine receptor subunit epsilon
- Purification:
- Affinity purification
- Background:
- Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
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