Product Datasheet
DGCR2 Polyclonal Antibody
Catalog Number: 28474
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P98153
NCBI Gene ID:9993
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DGCR2 (NP_005128.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- DGCR2; DGS-C; IDD; LAN; SEZ-12; integral membrane protein DGCR2/IDD
- Purification:
- Affinity purification
- Background:
- Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
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