Product Datasheet  
WIZ Antibody  
Catalog Number: 25241  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O95785
    Gene ID:58525
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 17 amino acid peptide near the carboxy terminus of human TFF3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Widely interspaced zinc finger motifs, ZNF803
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • At least four isoforms of WIZ are known to exist; this antibody will detect all four.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.



 
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