Product Datasheet
STEAP2 Antibody
Catalog Number: 24567
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 16 amino acid peptide from near the carboxy terminus of human STEAP2.
- other_names:
- Six transmembrane epithelial antigen of prostate 2
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- This STEAP2 antibody does not cross-react with other STEAP proteins.
- Applications:
- ELISA WB IHC
- Background:
- The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.
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