Product Datasheet  
Neurotrypsin Antibody  
Catalog Number: 24518  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P56730
    Gene ID:8492
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 23 amino acid peptide from near the amino terminus of human neurotrypsin.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • Motopsin, Protease serine 12, PRSS12, MRT1, BSSP3
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Applications:  
  • ELISA WB IHC
  • Background:  
  • Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.



 
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