Product Datasheet  
TLR3 Antibody  
Catalog Number: 24363  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • O15455
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • Toll-like receptor 3, CD283
  • Purification：  
  • Ion exchange chromatography purified
  • Specificity：  
  • Applications：  
  • ELISA WB ICC
  • Background：  
  • Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection. Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.



 
© Signalway Biotechnology All Rights Reserved.