Product Datasheet  
DR3 Antibody  
Catalog Number: 24028  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q93038
    Gene ID:8718
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a peptide corresponding to amino acids in extracellular domain of human DR3 precusor.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 59 kd
  • other_names：  
  • Wsl-1 Apo-3
  • Purification：  
  • DEAE purified
  • Specificity：  
  • Applications：  
  • ELISA WB ICC
  • Background：  
  • Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-κB activation.



 
© Signalway Biotechnology All Rights Reserved.