Product Datasheet  
SUCLA2 antibody  
Catalog Number: 23092  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9P2R7
    Gene ID:8803
  • Form of Antibody:  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen:  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 138 and 386 of human SUCLA2
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 50kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:50-1:500
    Immunofluorescence: 1:100-1:200
  • other_names:  
  • Purification:  
  • Purified by antigen-affinity chromatography.
  • Specificity:  
  • Applications:  
  • WB IHC IF
  • Background:  
  • Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]



 
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