Product Datasheet  
Glycine dehydrogenase antibody  
Catalog Number: 23002  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P23378
    Gene ID:2731
  • Form of Antibody:  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen:  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 442 and 693 of Human GLDC
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 113kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:50-1:500
    Immunofluorescence: 1:100-1:200
  • other_names:  
  • Purification:  
  • Purified by antigen-affinity chromatography.
  • Specificity:  
  • Applications:  
  • WB IHC IF
  • Background:  
  • The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]



 
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