Product Datasheet  
APE1 antibody  
Catalog Number: 22891  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P27695
    Gene ID:328
  • Form of Antibody：  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 36kd
    Western blotting: 1:500-1:3000
    Immunofluorescence: 1:100-1:200
  • other_names：  
  • APE; APE-1; APE1; APEN; APEX; APX; HAP1; REF-1; REF1
  • Purification：  
  • Affinity purified by Protein A.
  • Specificity：  
  • Applications：  
  • WB IF
  • Background：  
  • Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]



 
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