Product Datasheet  
RAD18 antibody  
Catalog Number: 22872  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9NS91
    Gene ID:56852
  • Form of Antibody：  
  • Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 229 of RAD18
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 56kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
  • other_names：  
  • Purification：  
  • Purified by antigen-affinity chromatography.
  • Specificity：  
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]



 
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