Product Datasheet  
PUF60 antibody  
Catalog Number: 22762  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9UHX1
    Gene ID:22827
  • Form of Antibody：  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 58kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
    Immunofluorescence: 1:100-1:200
  • other_names：  
  • FIR; PUF60; RoBPI
  • Purification：  
  • Purified by antigen-affinity chromatography.
  • Specificity：  
  • Applications：  
  • WB IHC IF
  • Background：  
  • The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq]



 
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