Product Datasheet  
MRCKalpha antibody  
Catalog Number: 22420  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q5VT25
    Gene ID:8476
  • Form of Antibody：  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 373 and 574 of Human CDC42BPA
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 186kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
    Immunofluorescence: 1:100-1:200
  • other_names：  
  • Purification：  
  • Affinity purified by Protein A.
  • Specificity：  
  • Applications：  
  • WB IHC IF
  • Background：  
  • The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq]



 
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