Product Datasheet  
CHMP5 antibody  
Catalog Number: 22389  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9NZZ3
    Gene ID:51510
  • Form of Antibody:  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen:  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 172 of Human CHMP5
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 25kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
  • other_names:  
  • Purification:  
  • Purified by antigen-affinity chromatography.
  • Specificity:  
  • Applications:  
  • WB IHC
  • Background:  
  • CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]



 
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