Product Datasheet
Lefty -A antibody
Catalog Number: 22375
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O00292
Gene ID:7044
- Form of Antibody:
- Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
- Storage:
- Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
- Immunogen:
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 25 and 351 of Lefty -A
- appl_detail:
- Predicted MW: 41kd
Western blotting: 1:500-1:3000
- Purification:
- Purified by antigen-affinity chromatography.
- Background:
- This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq]
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