Product Datasheet
Thrombomodulin(CD141) antibody
Catalog Number: 22197
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P07204
Gene ID:7056
- Form of Antibody:
- Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
- Storage:
- Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
- Immunogen:
- Synthetic peptide contain a sequence corresponding to a region within amino acids 512 and 575 of Thrombomodulin(CD141)
- appl_detail:
- Predicted MW: 60kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200
- other_names:
- TM; THRM; CD141
- Purification:
- Purified by antigen-affinity chromatography.
- Background:
- The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq]
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