Product Datasheet
CBS antibody
Catalog Number: 22188
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P35520|P0DN79
Gene ID:875
- Form of Antibody:
- Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
- Storage:
- Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
- Immunogen:
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 39 and 221 of CBS
- appl_detail:
- Predicted MW: 61kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:500
Immunofluorescence: 1:100-1:200
- Purification:
- Purified by antigen-affinity chromatography.
- Background:
- The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]
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