Product Datasheet  
HSD3a antibody  
Catalog Number: 22100  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P17516
    Gene ID:1109
  • Form of Antibody:  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage:  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen:  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 187 of HSD3a
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 37kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
  • other_names:  
  • 3-alpha-HSD
  • Purification:  
  • Purified by antigen-affinity chromatography.
  • Specificity:  
  • Applications:  
  • WB IHC
  • Background:  
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]



 
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