Product Datasheet  
NANS antibody  
Catalog Number: 22042  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9NR45
    Gene ID:54187
  • Form of Antibody：  
  • Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
  • Storage：  
  • Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
  • Immunogen：  
  • Recombinant protein fragment contain a sequence corresponding to a region within amino acids 54 and 341 of NANS
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 40kd
    Western blotting: 1:500-1:3000
    Immunohistochemistry: 1:100-1:250
  • other_names：  
  • SAS
  • Purification：  
  • Purified by antigen-affinity chromatography.
  • Specificity：  
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq]



 
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