Product Datasheet  
FHL2 Antibody  
Catalog Number: 21692  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q14192 NCBI Protein: NP_001034581.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C
  • Immunogen：  
  • Peptide sequence around aa.16~28 (I-L-R-E-E) derived from Human FHL2.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  •  Western blotting: 1:500�?:1000

  • other_names：  
  • SLIM3; AAG11; FHL-2; DRAL; aging-associated gene 11
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total FHL2 protein.
  • Applications：  
  • WB
  • Background：  

  •  May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. 

    Genini M., Schwalbe P., Scholl F.A., Remppis A., Mattei M.-G., Schaefer B.W.DNA Cell Biol. 16:433-442(1997)
    Tanahashi H., Tabira T.Hum. Mol. Genet. 9:2281-2289(2000)



 
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