Product Datasheet  
C/EBPb Antibody  
Catalog Number: 21675  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P17676
    NCBI Protein: NP_005185.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.336~340(E-P-L-L-A) derived from Human C/EBPb.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 36kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • IL6DBP; CRP2; TCF5; LAP; NF-IL6
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total C/EBPb protein.
  • Applications：  
  • WB
  • Background：  
  • Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation

    Buck M., Poli V., Hunter T., Chojkier M. Mol. Cell 8:807-816(2001)
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J. Mohammed S.Anal. Chem. 81:4493-4501(2009)



 
© Signalway Biotechnology All Rights Reserved.