Product Datasheet  
CUEDC2 Antibody  
Catalog Number: 21673  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9H467
    NCBI Protein: NP_076945.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.262~266(D-V-R-N-P) derived from Human CUEDC2.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 32kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • C10orf66; bA18I14.5;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total CUEDC2 protein.
  • Applications：  
  • WB
  • Background：  

  • Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

    Zhang P.-J., Zhao J., Li H.-Y. EMBO J. 26:1831-1842(2007)




 
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